Fig. 3 | Scientific Reports

Fig. 3

From: Detection of moderate to high antiphospholipid antibodies by chemiluminescence meets 2023 APS classification criteria

Fig. 3The alternative text for this image may have been generated using AI.

Odds ratios for moderate and high titers of aCL and aβ2GP1 in association with thrombosis, pregnancy morbidity and thrombocytopenia. The results were presented in the form of odds ratios, comparing high and moderate titers to low titers in relation to thrombosis, pregnancy morbidity and thrombocytopenia, along with their respective 95% confidence intervals. High titers for the IgG and IgM isotypes of aCL and aβ2GP1 were defined as values exceeding 80 U in ELISA. In CIA, the thresholds varied among antibodies: 446.20 CU for aCL IgG, 332.60 CU for aCL IgM, 2733.00 CU for anti-β2GPI IgG, and 36.00 CU for anti-β2GPI IgM, respectively. Moderate titers are defined as values falling below the previously mentioned high thresholds and ranging above 40 U in ELISA. In CIA, the thresholds differed among antibodies: 116.70 CU for aCL IgG, 39.75 CU for aCL IgM, 409.60 CU for anti-β2GPI IgG, and 25.75 CU for anti-β2GPI IgM, respectively.

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