Fig. 5 | Scientific Reports

Fig. 5

From: Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies

Fig. 5

Effect of FIN, HCQ, and a combination of both on the protein expression level of ERK1/2, EGFR, and STAT3 in rats’ prostatic tissue. The expression level of ERK1/2 (A), densitometry analysis of p-EGFR to t-EGFR (B) and p-STAT-3 to t-STAT-3 (C), and western blotting images of EGFR and STAT-3 in both phosphorylated and total forms (D). One-way ANOVA, followed by Tukey’s multiple comparison test, was used for statistical analysis. *: Statistically significant at P < 0.05, ***: Statistically significant at P < 0.001, ****: Statistically significant at P < 0.0001.

Back to article page