Table 3 Comparative diagnostic performance of the research assay and InSignia assay in detecting viral infection (n = 38).

From: Evaluating the InSignia IFI27 expression assay for detecting viral respiratory infection compared to a traditional gene normalisation assay

Metric

Research assay

InSignia assay

Sensitivity [%, (95% CI)]

75.86 (56.46–89.70)

93.10 (77.23–99.15)

Specificity [%, (95% CI)]

100 (66.37–100)

100 (66.37–100)

Positive Predictive Value [%, (95% CI)]

100 (84.56–100)

100 (87.23–100)

Negative Predictive Value [%, (95% CI)]

56.25 (40.28–71.02)

81.82 (54.16–94.49)

Accuracy [%, (95% CI)]

81.58 (65.67–92.26)

94.74 (82.25–99.36)

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