Table 13 Drugs requiring TDM predicted by MEN as CYP450 Inhibitors from the 15 selected drugs (West China Hospital).

From: MEN: leveraging explainable multimodal encoding network for precision prediction of CYP450 inhibitors

Drugs

Inhibitor of CYP450 enzyme

Fluoxetine (Prozac)

CYP2D6

Diltiazem

CYP3A4

Verapamil

CYP3A4

Ketoconazole

CYP3A4, CYP2C9, CYP2C19

Amiodarone

CYP3A4, CYP2C9, CYP2D6, CYP1A2

Ritonavir

CYP3A4, CYP2D6, CYP2C9, CYP1A2

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