Table 1 Molar concentrations (mean ± SD) for aminoacids measured in concurrent samples of plasma and sweat, along with their molecular weight (MW) and logp, with p-values for comparisons between the means by paired t-test.

From: Investigation of effects of collection conditions on amino acid concentrations in sweat and correlations with their Circulating levels in plasma

Analyte

MW (Da)

LogP value

Plasma (µM)

Sweat (µM)

P (for diff)

Alanine

89

− 3.0

320.25 ± 112.69

937.40 ± 404.07

< 0.0003

Arginine

174

− 4.2

47.36 ± 30.94

97.01 ± 67.42

< 0.0003

Asparagine

132

− 3.4

45.53 ± 18.58

73.03 ± 42.40

< 0.0003

Aspartic acid

133

− 2.8

4.20 ± 3.14

204.21 ± 101.18

< 0.0003

Citrulline

175

− 4.3

20.95 ± 7.64

440.56 ± 227.80

< 0.0003

Glutamic acid

147

− 3.7

46.42 ± 35.06

133.01 ± 66.78

< 0.0003

Glutamine

146

− 3.1

445.16 ± 19.01

19.01 ± 12.67

< 0.0001

Glycine

75

− 3.2

200.12 ± 99.60

1390.06 ± 643.91

< 0.0003

Histidine

155

− 3.2

69.33 ± 22.59

367.14 ± 198.78

< 0.0003

Isoleucine

131

− 1.7

55.20 ± 27.10

95.64 ± 44.95

< 0.0003

Leucine

131

− 1.5

105.95 ± 45.97

97.68 ± 46.22

N.S.

Lysine

146

− 3.0

152.85 ± 63.40

95.08 ± 46.75

< 0.0001

Methionine

149

− 1.9

19.22 ± 7.66

8.64 ± 5.22

< 0.0001

Ornithine

132

− 4.4

79.63 ± 36.73

302.76 ± 139.41

< 0.0003

Phenylalanine

165

− 1.5

50.38 ± 16.43

58.67 ± 27.27

N.S.

Proline

115

− 2.5

158.50 ± 58.60

159.79 ± 74.58

N.S.

Serine

105

− 3.1

86.79 ± 36.77

2080.44 ± 809.31

< 0.0003

Threonine

119

− 2.9

104.64 ± 41.66

452.06 ± 211.08

< 0.0003

Tryptophan

204

− 1.1

39.28 ± 12.32

43.27 ± 20.25

N.S.

Tyrosine

181

− 2.3

53.05 ± 18.71

106.57 ± 47.27

< 0.0003

Valine

117

− 2.3

195.45 ± 69.91

205.27 ± 96.43

N.S.

Trans-Hydroxyproline

131

− 3.2

8.96 ± 5.41

0.28 ± 0.17

< 0.0001

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