Fig. 3 | Scientific Reports

Fig. 3

From: Oxidative stress gene expression in ulcerative colitis: implications for colon cancer biomarker discovery

Fig. 3

Differential expression analysis of three datasets. (A–C) Volcano plots illustrating the results of the differential analysis between disease and control groups in the TCGA-COADREAD dataset (A), GSE74602 dataset (B), and GSE4183 dataset (C). (D) Venn diagram showcasing the overlap of differentially expressed genes (DEGs) in the three datasets. (E) Venn diagram highlighting the common differentially expressed genes (co-DEGs) and oxidative stress-related genes (OXSRGs). (F) Venn diagram presenting the intersection of COX univariate screening results and OXSRDEGs. (G–I) Heatmaps depicting the expression of OXSRDEGs in disease and control groups for TCGA-COADREAD (G), GSE74602 (H), and GSE4183 (I). TCGA, The Cancer Genome Atlas; UC, Ulcerative colitis; COADREAD, Colorectal carcinoma; DEGs, differentially expressed genes; co-DEGs, common DEG; OXSRGs, Oxidative stress-related genes; OXSRDEGs, Oxidative stress-related differentially expressed genes.

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