Fig. 5 | Scientific Reports

Fig. 5

From: Oxidative stress gene expression in ulcerative colitis: implications for colon cancer biomarker discovery

Fig. 5

GSEA Enrichment Analysis of TCGA-COADREAD Dataset. (A) Illustrates the primary six biological features of gene enrichment between groups in the TCGA-COADREAD dataset. (B–G) Highlight the significant enrichment of genes in the TCGA-COADREAD dataset within WP_GLUCURONIDATION (B), KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION (C), WP_PEPTIDE_GPCRS (D), REACTOME_BIOLOGICAL_OXIDATIONS (E), REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION (F), and REACTOME_GPCR_LIGAND_BINDING (G). GSEA, Gene Set Enrichment Analysis; TCGA, The Cancer Genome Atlas; COADREAD, Colorectal Carcinoma. The significant enrichment criteria for GSEA were P.adj < 0.05 and FDR value (q.value) < 0.05.

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