Fig. 7
Boxplot Expression Analysis and ROC Curves of OXSRDEGs in TCGA-COADREAD. (A) Presents a boxplot illustrating the expression comparison of OXSRDEGs in the TCGA-COADREAD dataset. (B–M). Showcase ROC curves for individual OXSRDEGs (BMP5 (B), CXCL1 (C), CXCL11 (D), CXCL2 (E), MGP (F), MMP1 (G), MMP10 (H), MMP3 (I), NFE2L3 (J), PPARGC1A (K), RNASE1 (L), TIMP1 (M)) in the TCGA-COADREAD dataset. In the legend, “ns” indicates P ≥ 0.05, signifying no statistical significance; *, denoting P < 0.05, implies statistical significance; ** indicates P < 0.01, representing high statistical significance; *** signifies P < 0.001, indicating extremely high statistical significance. A higher AUC in the ROC curve suggests a more effective diagnosis, with AUC between 0.5 and 0.7 indicating low accuracy, AUC between 0.7 and 0.9 indicating moderate accuracy, and AUC above 0.9 indicating high accuracy. TCGA, The Cancer Genome Atlas; COADREAD, Colorectal Carcinoma; OXSRDEGs, Oxidative Stress-Related Differentially Expressed Genes.
