Fig. 8

Boxplot Expression Analysis and ROC Curves of OXSRDEGs in GSE74602. (A) The boxplot comparison of OXSRDEGs’ expression in the GSE74602 dataset (COADREAD/Control) is illustrated. B-M. The ROC curves for OXSRDEGs (BMP5 (B), CXCL1 (C), CXCL11 (D), CXCL2 (E), MGP (F), MMP1 (G), MMP10 (H), MMP3(I), NFE2L3(J), PPARGC1A (K), RNASE1(L), TIMP1(M)) in the GSE4183 dataset are presented. ‘ns’ indicates P ≥ 0.05, denoting no statistical significance; * denotes P < 0.05, indicating statistical significance; ** signifies P < 0.01, representing high statistical significance; *** indicates P < 0.001, highlighting extremely high statistical significance. The proximity of the AUC in the ROC curve to 1 correlates with improved diagnostic performance. An AUC ranging from 0.5 to 0.7 suggests low accuracy; an AUC between 0.7 and 0.9 indicates moderate accuracy; an AUC exceeding 0.9 signifies high accuracy. OXSRDEGs stands for Oxidative Stress Related Differentially Expressed Genes; COADREAD denotes Colorectal Carcinoma; UC refers to Ulcerative Colitis.