Fig. 3 | Scientific Reports

Fig. 3

From: Synthesis, characterization, anti-proliferative, and apoptotic activity of a novel quinazoline-containing 1,2,3-triazole toward three human cancer cells

Fig. 3The alternative text for this image may have been generated using AI.

A549, MCF7, and K562 cells treated with 4-TCPA and Erlotinib (as a positive control) were subjected to a quantitative annexin V/PI double staining test to measure apoptosis. (A) 4-TCPA caused apoptosis in A549 (a,b,c), MCF7 (d,e,f), and K562 (g,h,i) cells in a dose- and time-dependent manner, according to flow cytometric analysis in. (B) The graph shows the statistical quantification of data A549 (a), MCF7 (b) and K562 (c) following 4-TCPA treatment. Apoptosis analysis using flow cytometry revealed a time- and dose-dependent increase in early and late apoptotic cells. The data reflect the mean plus standard deviation (SD) of three separate studies. Comparing each group to its control resulted in ***p < ****p < 0.0001.

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