Fig. 4

Assessment of caspase 3/7 enzymatic activities. The activation of caspase 3/7 was evaluated in A549 (a), MCF7 (b) and K562 (c) cell lines after exposure to the 4-TCPA at indicated time point (72h), as explained in the material and method. Plots represent caspase 3/7 enzymatic activity (mU/mL) of the treated cells relative to the untreated groups and positive control (Erlotinib). The results are expressed as mean ± SD (n = 3) (****p < 0.0001 (A549), **p < 0.0013 (MCF7), **p < 0.0023 (K562)) versus positive control.