Fig. 5 | Scientific Reports

Fig. 5

From: Synthesis, characterization, anti-proliferative, and apoptotic activity of a novel quinazoline-containing 1,2,3-triazole toward three human cancer cells

Fig. 5The alternative text for this image may have been generated using AI.

Measurement of mRNA expression levels following 4-TCPA exposure. At the designated time, 4-TCPA with an IC50 concentration was treated with A549 (a), MCF7 (b), K562 (c), cells. qRT-PCR was used to assess changes in the transcript levels of Akt, mTOR, MAPK, PIK3CA, EGFR and VEGFR2. Plots represent Akt, mTOR, MAPK, PIK3CA, EGFR and VEGFR2 expression levels of the treated cells relative to the control (B2M). The findings are presented as the mean SD (n = 3); (****p < 0.0001 (A549), (MCF7) and (K562) VEGFR2) versus control.

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