Table 3 Clinicopathological characteristics of LUSC patients(n = 70).
From: Low expression of SGCA promotes lung squamous cell carcinoma malignant progression
Characteristics | Low expression of SGCA | High expression of SGCA | P value |
|---|---|---|---|
n | 52 | 18 | |
Gender, n (%) | 0.764 | ||
Female | 8 (11.4%) | 4 (5.7%) | |
Male | 44 (62.9%) | 14 (20%) | |
Age, mean ± SD | 68.019 ± 6.5334 | 67.667 ± 7.3485 | 0.849 |
Pathologic T stage, n (%) | < 0.001 | ||
1 | 18 (25.7%) | 17 (24.3%) | |
2 | 25 (35.7%) | 1 (1.4%) | |
3 | 6 (8.6%) | 0 (0%) | |
4 | 3 (4.3%) | 0 (0%) | |
Pathologic N stage, n (%) | 0.218 | ||
0 | 37 (52.9%) | 17 (24.3%) | |
1 | 7 (10%) | 1 (1.4%) | |
2 | 5 (7.1%) | 0 (0%) | |
3 | 3 (4.3%) | 0 (0%) | |
Pathologic M stage, n (%) | 0.714 | ||
1 | 3 (4.3%) | 0 (0%) | |
0 | 49 (70%) | 18 (25.7%) | |
Pathologic Stage, n (%) | 0.020 | ||
1 | 28 (40%) | 17 (24.3%) | |
3 | 11 (15.7%) | 0 (0%) | |
2 | 10 (14.3%) | 1 (1.4%) | |
4 | 3 (4.3%) | 0 (0%) | |
Number pack years smoked, median (IQR) | 20 (3.75, 40) | 12.5 (0, 35) | 0.225 |
CEA (ng/ml), median (IQR) | 3.64 (2.35, 6.03) | 3.09 (2.43, 4.71) | 0.676 |
CYFRA21-1 (ng/ml), median (IQR) | 2.61 (1.665, 4.805) | 1.4 (0.86, 1.7025) | < 0.001 |
SCC (ng/ml), median (IQR) | 0.95 (0.7, 1.525) | 1 (0.9, 1.2) | 0.912 |
NSE (ng/ml), median (IQR) | 4.05 (3.18, 5.145) | 3.69 (3.3175, 4.335) | 0.600 |
Blood Ca2+(mmol/l), median (IQR) | 2.235 (2.1875, 2.3325) | 2.26 (2.175, 2.345) | 0.971 |
Lesion CT value Max, median (IQR) | 73.5 (49.75, 93.5) | 81.5 (54.75, 89.5) | 0.877 |
Lesion CT value Min, median (IQR) | 10.5 (-10.5, 23.25) | -13 (-24.5, 13.5) | 0.148 |
Mean lesion CT value, mean ± SD | 41.654 ± 19.211 | 30.222 ± 24.967 | 0.048 |
Cystatin C (mg/L), median (IQR) | 0.88 (0.76, 1) | 0.8 (0.75, 0.94) | 0.307 |
Creatinine (umol/L), median (IQR) | 69.15 (62.75, 81.075) | 43.99 (37.367, 59.145) | < 0.001 |
Uric Acid (umol/L), median (IQR) | 301.5 (247, 356.25) | 305.5 (270.75, 327.5) | 0.830 |
LDH (u/l), median (IQR) | 178.5 (161.75, 208.75) | 178.5 (149.75, 202.25) | 0.619 |
