Fig. 4
(A) The correlation of SUVmax values obtained with 68Ga-SC691 and 68Ga-PSMA-11 in various lesions was assessed using scatter plot analysis. Regression lines (solid lines), 95% confidence intervals (thin dashed lines), and 95% prediction intervals (thick dashed lines) are displayed on the scatter plots. All data points were contained within the 95% prediction intervals. Strong correlations were observed for primary PCa lesions, bone metastases, and lymph nodes metastases, suggesting comparable diagnostic accuracy of the two radiotracers. (B) Agreement between 68Ga-PSMA-11 and 68Ga-SC691 SUVmax measurements in different lesions was evaluated using Bland-Altman analysis. The mean bias (difference between 68Ga-PSMA-11 and 68Ga-SC691 SUVmax values) is indicated by a red dashed line, and the 95% limits of agreement (LOA) are represented by thin dashed lines. The mean bias ± standard deviation was − 4.7 ± 3.0 for primary PCa lesions, -4.1 ± 3.3 for bone metastases, and − 5.4 ± 5.1 for lymph nodes metastases. All data points were within the 95% LOA, confirming good agreement between the two radiotracers across all lesion types.
