Fig. 1
From: Causal association between oral microbiota and oral cancer: a mendelian randomization study
Schematic representation of the two-sample bi-directional Mendelian randomization analysis. Mendelian randomization was used to evaluate the causal links between 43 microbial taxa and oral cancer. Three key assumptions of Mendelian randomization: (1) genetic variants must be associated with exposures, (2) genetic variants must not be associated with confounders, and (3) genetic variants must affect outcomes only through exposures, not through other pathways.
