Table 1 Demographic characteristics and ocular surface parameters in patients with DED, glaucoma, and healthy controls.
From: Reference genes validation in tear fluid for RNA analysis in ocular surface disease
Control (n = 8) | DED (n = 8) | Glaucoma (n = 8) | |
|---|---|---|---|
Age (mean ± SD) | 36.75 ± 11.34 | 56.63 ± 13.89 | 72.25 ± 7.01 |
Sex (% female), n | 50.0% (n = 4) | 37.5% (n = 3) | 37.5% (n = 3) |
Ethnicity (%) | |||
Hispanic or Latino | 87.5% (n = 7) | 62.5% (n = 5) | 37.5% (n = 3) |
Non-Hispanic or Latino | 12.5% (n = 1) | 37.5% (n = 3) | 62.5% (n = 5) |
Race (%) | |||
White | 100.0% (n = 8 | 100.0% (n = 8 | 62.5% (n = 5) |
Black or African American | 0.0% (n = 0) | 0.0% (n = 0) | 37.5% (n = 3) |
Clinical characteristics | |||
OSDI score (mean ± SD) | 5.35 ± 4.934 | 31.25 ± 15.84 (p = 0.0024) | 38.89 ± 17.53 (p = 0.0002) |
NEI staining score (mean ± SD) | 0.250 ± 0.462 | 2.625 ± 0.916 (p = 0.0130) | 4.500 ± 2.449 (p < 0.0001) |
NIKBUT first (s, mean ± SD) | 8.688 ± 1.214 | 5.232 ± 2.647 (p = 0.0118) | 7.112 ± 2.709 (p = 0.348) |
Redness (Jenvis scale, mean ± SD) | 0.862 ± 0.238 | 1.650 ± 0.459 (p = 0.0013) | 1.78 ± 0.443 (p = 0.0011) |
Meibography score (mean ± SD) | 0.250 ± 0.534 | 1.571 ± 1.134 (p = 0.0279) | 1.438 ± 1.116 (p = 0.0413) |
