Table 3 Optimization of solidified SNEDDS based on particle size and yield (mean ± SD, n = 3).

From: Fabrication and evaluation of solidified nanoemulsion designs for systemic delivery of atorvastatin through the lung

Code

Particle size distribution (µm)

Yield (%)

 

D10

D50

D90

SF1

The wall material was insufficient to dry nanoemulsion by spray drying process

SF2

15.29 ± 0.81

23.31 ± 1.43

47.73 ± 2.12

46.37 ± 3.16

SF3

20.66 ± 1.10

37.81 ± 2.07

76.11 ± 3.39

52.88 ± 2.24

SF4

8.72 ± 0.45

10.21 ± 0.44

26.59 ± 1.21

37.49 ± 2.28

SF5

11.28 ± 0.66

15.58 ± 0.61

36.61 ± 2.71

45.56 ± 3.04

SF6

16.93 ± 1.04

23.21 ± 1.19

42.36 ± 2.89

50.12 ± 2.15

SF7

The wall material was insufficient to dry nanoemulsion by spray drying process

SF8

1.15 ± 0.03

2.66 ± 0.22

5.48 ± 0.94

52.77 ± 2.47

SF9

6.15 ± 0.51

15.48 ± 1.11

32.66 ± 2.51

56.68 ± 3.61

SF10

0.94 ± 0.01

2.02 ± 0.12

4.55 ± 0.63

62.33 ± 3.96