Fig. 2 | Scientific Reports

Fig. 2

From: PSD3, regulated by PKM2, endows growth and metastasis advantages in esophageal squamous cell carcinoma by modulating EMT progression

Fig. 2

PSD3 promotes proliferation, migration, and invasion of ESCC cells in vitro. A, Endogenous expression of PSD3 in ESCC cell lines. B, C, Assayed was the variation of PSD3 expression in Eca-109 cells transfected with Lv-overexpress-PSD3 and in KYSE-150 cells transfected with Lv-shRNA-PSD3 by Western blot. D, Assayed was the proliferation by MTT assay. E, Assayed was the migration by Wound Healing method; Magnification: 100×, scale bar represents 100 μm correspondingly. F, Assayed were the migration and invasion by Transwell assay; Magnification: 200×, scale bar represents 50 μm correspondingly. *represents comparison with the Blank control, *p < 0.05, **p < 0.01, and ***p < 0.001; \(^{\blacktriangle}\) represents comparison with scramble, \(^{\blacktriangle}\) p < 0.05, \(^{\blacktriangle\blacktriangle}\) p < 0.01, and \(^{\blacktriangle\blacktriangle\blacktriangle}\) p < 0.001.

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