Fig. 3 | Scientific Reports

Fig. 3

From: Diagnosing malignant transformation potential in oral submucous fibrosis with leukoplakia: an approach utilizing deoxyribonucleic acid image cytometry

Fig. 3

DNA-ICM analysis results of three different ratios. (A-C) An OSF + OLK lesion with a DI value of more than 3 nuclei ≥ 2.3 was diagnosed as mild abnormal proliferation. (D-F) An OSF + OLK with focal carcinomatosis with a DI value of more than 3 nuclei ≥ 2.3 was diagnosed as severe abnormal proliferation. (G-I) An OSCC lesion with a DI value of more than 3 nuclei ≥ 2.3 was diagnosed as severe abnormal proliferation. (A), (D), (G) are the morphology of aneuploid cells and normal cells (Feulgen staining, lens × 100). (B), (E), (H) are the morphology of aneuploid cells and normal cells (Feulgen staining, lens × 400). (C), (F), (I) are scatter plots showing the number of cells at different DI.

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