Fig. 1
From: Metagenomic analysis uncovers novel hepadnaviruses and nackednaviruses
Classification and novel display method for hepadnaviruses and nackednaviruses. (A) Phylogenetic trees depicting reference hepadnaviruses and nackednaviruses, with representative viruses and their hosts highlighted in red. Nacked = nackednavirus, Herpeto = herpetohepadnavirus, Avi = avihepadnavirus, Para = parahepadnavirus, Meta = metahepadnavirus, Ortho = orthohepadnavirus. Scale bar indicates substitutions per site. (B) An unrooted tree layout illustrating novel hepadnaviruses and nackednaviruses identified in this study. (C) A schematic comparison of the conventional EcoRI-origin numbering system for the HBV genome, which starts at the EcoR1 restriction site (G/AATTC, where the first T is nucleotide 1, green pentagram), and the HBc-origin (red pentagram). (D) A representation of the viral genome based on the HBc-origin for human HBV (GenBank: U95551), an orthohepadnavirus; frog hepadnavirus (GenBank: KX058435), a herpetohepadnavirus; and rockfish nackednavirus (GenBank: MH158726), a nackednavirus.
