Table 1 Histopathological characteristics of 47 tumors from 47 patients.

From: Immunohistochemical expression of smoothened in periocular basal cell, squamous cell and sebaceous carcinomas

Tumor type

n

Key Features

Basal cell carcinoma (BCC)

17

EADO stage, n*

-IIB: 10

-IIIB: 7

No patients in stages I, IIA, IIIA, IIIC, or IV

Squamous cell carcinoma (SCC)

15

Differentiation, n

-Well differentiated: 4

-Moderately differentiated: 9

-Poorly differentiated: 2

AJCC 8th Edition T-category, n†

-T1a: 5

-T1b: 6

-T2a: 3

-T3c: 1

Sebaceous carcinoma (SEB)

15

Differentiation, n

-Poorly differentiated: 6

-Moderately differentiated: 9

Pagetoid spread

-Present in 6/15 (40%)

WHO Grade, n‡

-Grade I: 8

-Grade II: 3

-Grade III: 4

Growth patterns, n

-Lobular: 11

-Comedocarcinoma: 1

-Papillary: 0

-Mixed: 3

  1. *According to the European Association for Dermato-Oncology (EADO) proposal for an operational staging system adapted to basal cell carcinomas20. †According to the American Joint Committee on Cancer (AJCC) staging system for eyelid carcinomas (8th Edition)21. ‡The WHO grading system for sebaceous carcinoma ranges from well-demarcated tumors (Grade I) to highly invasive growth patterns (Grade III)22.