Table 3 Insulin function associations with functional brain network topology.

From: Insulin resistance, cognition, and functional brain network topology in older adults with obesity

Ā 

Global efficiency

Local efficiency

β

SE

p

β

SE

p

HOMA2-IR

Ā Central executive network

āˆ’ā€‰0.0010

0.0006

0.097

āˆ’ā€‰0.0005

0.0003

0.104

Ā Hippocampus

āˆ’ā€‰0.0004

0.0011

0.724

0.0035

0.0014

0.011

R

Ā Central executive network

0.0002

0.0003

0.380

0.0000

0.0002

0.897

Ā Hippocampus

0.0002

0.0006

0.752

āˆ’ā€‰0.0002

0.0007

0.782

  1. HOMA2-IR homeostatic model assessment for insulin resistance (a measure of peripheral insulin resistance).
  2. R neuronal insulin resistance factor (a measure of neuronal insulin signaling abnormalities).
  3. SE standard Error.