Table 1 Demographic and Baseline Characteristics.

From: Risk of Long COVID in hospitalized individuals treated with remdesivir for acute COVID-19

Characteristic

Total

(N = 52,006)

Remdesivir-exposed

(n = 17,164)

Unexposed

(n = 34,842)

SMD

Sex, n (%)

   

0.06

  Male

25,484 (49.0)

8727 (50.8)

16,757 (48.1)

 

  Female

26,522 (51.0)

8437 (49.2)

18,085 (51.9)

 

Age, years, mean (SD)

59 (18.3)

57 (16.4)

60 (19.1)

0.13

Maximal level of oxygen support on Day 0 or 1, n (%)

   

0.23

  Room/ambient air

33,810 (65.0)

10,006 (58.3)

23,804 (68.3)

 

  Low-flow oxygen

10,458 (20.1)

4189 (24.4)

6269 (18.0)

 

  High-flow oxygen/noninvasive ventilation

5265 (10.1)

2209 (12.9)

3056 (8.8)

 

  ECMO/invasive mechanical ventilation

2473 (4.8)

760 (4.4)

1713 (4.9)

 

ICU admission on Day 0 or 1, n (%)

25,221 (48.5)

8608 (50.2)

16,613 (47.7)

0.05

Concomitant medications received on Day 0 or 1, n (%)

  Corticosteroids

33,849 (65.1)

16,297 (94.9)

17,552 (50.4)

1.16

  Immunomodulators

1860 (3.6)

1390 (8.1)

470 (1.3)

0.32

  Convalescent plasma

2730 (5.2)

2070 (12.1)

660 (1.9)

0.41

  Anticoagulants

13,949 (26.8)

3161 (18.4)

10,788 (31.0)

0.29

Immunocompromised* during baseline period, n (%)

20,246 (38.9)

5980 (34.8)

14,266 (40.9)

0.13

Moderately-to-severely immunocompromised during baseline period, n (%)

5673 (10.9)

1686 (9.8)

3987 (11.4)

0.05

  1. ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; NIH, National Institutes of Health; SMD, standardized mean difference.
  2. *Immunocompromised by modified NIH definition (Table 1) 30. This variable was not accounted for in propensity score weighting.