Table 1 Recent brain tumor grading studies via traditional ML and DL methods, as well as statistical modeling methods on brain MRI images.

From: Stochastic differential equation modeling approach for grading astrocytomas on brain MRI images

References

Year

Data

Method

Application

Machine Learning Methods

Noviandy et al.11

2025

Glioma

Light Gradient Boosting Machine

Distinguishing low grade tumors with grade IV (Acc. = 0.89)

Kumar et al.7

2023

Glioma

Radiomics features with SVM, RF, Gradient Boost, Naïve Bayes, and AdaBoost classifiers

Grading of tumor into high and low grades (Acc. = 0.83)

Vijithananda et al.8

2023

Glioma

Texture features with Logistic Regression, LDA, Decision Tree, Gaussian Naïve Bayes,

SVM, KNN, and RF classifiers

Grading of tumor into II, III, and IV (Acc. = 0.88)

Chen et al.4

2021

Astrocytoma

Radiomics features with SVM, RF, and LDA classifiers

Distinguishing grade I and II from III (Acc. = 0.77)

Tian et al.9

2019

Astrocytoma

Texture features with LDA classifier

Distinguishing grade III from IV (Acc. = 0.97)

Dong et al.10

2018

Astrocytoma

Quantitative radiomic features with Decision Tree classifier

Distinguishing grade I from IV (Acc. = 0.87)

DeepLearning Methods

Goceri et al.17

2025

Glioma

A network combination of both Convolutional Neural Networks (CNNs) and transformers

Grading of tumor into high and low grades (Acc. = 0.99)

Usuzaki et al.29

2024

Glioma

variable Vision Transformer (vViT)

Grading of tumor into II, III, and IV (Acc. = 0.84)

Wu et al.30

2024

Glioma

An end-to-end multi-task deep learning (MDL) pipeline

Grading of tumor into II, III, and IV (Acc. = 0.83)

Vale et al.31

2024

Glioma

Resnet50

Grading of tumor into II, III, and IV (Acc. = 0.62)

Shargunam et al.13

2023

Glioma

A novel Convolutional neural network-based SVM

Grading of tumor into high and low grades (Acc. = 0.99)

Trong et al.32

2023

Glioma

combination of complex network and U-Net

Grading of tumor into high and low grades (Acc. = 0.99)

Gilanie et al.5

2020

Astrocytoma

CNN

Grading of tumor into I, II, III, and IV (Acc. = 0.96)

Gutta et al.14

2020

Glioma

Deep CNN

Grading of tumor into I, II, III, and IV (Acc. = 0.87)

Naser et al.15

2020

Glioma

CNN

Distinguishing grade II from III (Acc. = 0.89)

George et al.1

2019

Astrocytoma

Deep Learning Neural Network

Grading of tumor into I, II, III, and IV (Acc. = 0.91)

Lo et al.6

2019

Glioma

Deep CNN

Grading of tumor into II, III, and IV (Acc. = 0.97)

Statistical Modeling

Bian et al.20

2022

Normal

Improved gaussian Mixture model

Brain tissue segmentation and classification

Cheng et al.21

2022

Normal

Finite Skew student’s-t Mixture model

Brain tissue segmentation

Togao et al.33

2020

Brain tumor

Gamma Distribution (GD) model

Differentiation of primary central nervous system lymphomas and glioblastomas

Pravitasari et al.22

2020

Brain tumor

Bayesian Neo-Normal Mixture model

Brain Tumor Segmentation

Pravitasari et al.23

2019

Brain tumor

Fernandez-Steel Skew Normal Mixture model

Brain Tumor Segmentation

Peis et al.24

2017

Normal

Hidden Markov

random fields with alpha-stable distributions

Brain tissue segmentation

Xia et al.25

2016

Normal

Local variational

Gaussian mixture models

Brain tissue segmentation

Chua et al.26

2015

Multiple Sclerosis

Linear mixed models

Modeling whole

brain lesion volume and atrophy

Balafar et al.27

2014

Normal

Gaussian Mixture model

Brain tissue segmentation

Salas-Gonzalez et al.34

2013

Normal

Bayesian alpha-stable mixture model

Brain tissue segmentation

Vadaparthi et al.35

2011

Normal

Skew Gaussian Distribution

Brain tissue segmentation

  1. Acc.: accuracy; SVM: support vector machine; RF: random forest; LDA: linear discriminant analysis; KNN: K-Nearest Neighbor