Fig. 3

Pathway analysis. (A) Bubble map of the enriched Significant classify KEGG pathway. (B) Bubble map of the enriched Secondary classify KEGG pathway. Environmental Information Processing: E, Genetic Information Processing: G, Human Diseases: H, Metabolism: M, Organismal Systems: O. (C) Pathway Impact plot of differential metabolites calculated by Out degree centrality method. (D) Pathway Impact plot of differential metabolites calculated by Betweenness centrality method. (E) Differential abundance score plot for differential metabolites.