Table 1 Relationship between uH2B expression and clinicopathological parameters in LUAD.

From: Effect of defective H2B ubiquitination on the malignancy and repair of DNA double breaks and its significance in lung adenocarcinoma

Clinicopathological

variables

n

uH2B

χ2

P

Low

expression

High

expression

(n = 139)

(n = 24)

Gender

 Male

92

81

11

1.288

0.256

 Female

71

58

13

Age(years)

 < 60

68

57

11

0.196

0.658

 ≥ 60

95

82

13

Smoking

 YES

78

69

9

1.209

0.272

 NO

85

70

15

T staging

 T1 + T2

104

85

19

2.287

0.09

 T3 + T4

59

54

5

N staging

 NO + N1

98

81

17

1.34

0.246

 N2 + N3

65

58

7

M staging

 MO

155

132

23

0.033

0.856

 M1

8

7

1

Clinical staging

 I + II

81

64

17

5.031

0.025 *

 III + IV

82

75

7

Recurrence

 YES

38

37

1

5.771

0.016*

 NO

125

102

23

EGFR

 Fusion

46

40

6

0.143

0.205

 Unfused

64

54

10

  1. uH2B: Monoubiquitination of histone H2B at lysine 120.