Table 2 Survival Patterns of Advanced Renal Cell Carcinoma Patients Across Both Age Groups in the ICI and Non-ICI Eras.
Parameters | <65 years group | \(\ge\)65 years group | ||||
|---|---|---|---|---|---|---|
(median months) | (median months) | |||||
Non-ICI era | ICI era | Log rank | Non-ICI era | ICI era | Log rank | |
(7 months) | (16 months) | P value | (6 months) | (13 months) | P value | |
Sex | ||||||
Male | 7 | 17 | 0.0001 | 6 | 14 | 0.0001 |
Female | 7 | 15 | 0.0001 | 6 | 11 | 0.0001 |
Race | ||||||
White | 7 | 17 | 0.0001 | 6 | 13 | 0.0001 |
Black | 6 | 11 | 0.0001 | 6 | 9 | 0.0001 |
Others | 8 | 18 | 0.0001 | 6 | 16 | 0.0001 |
Marital status | ||||||
Yes | 7 | 18 | 0.0001 | 6 | 14 | 0.0001 |
Others | 7 | 14 | 0.0001 | 6 | 11 | 0.0001 |
Laterality | ||||||
Both side | 5 | 6 | 0.49 | 4 | 4 | 0.135 |
Right side | 7 | 17 | 0.0001 | 6 | 13 | 0.0001 |
Left side | 7 | 16 | 0.0001 | 6 | 14 | 0.0001 |
Surgery status | ||||||
Performed | 9 | 22 | 0.0001 | 10 | 21 | 0.0001 |
Others | 5 | 7 | 0.0001 | 4 | 6 | 0.0001 |
Radiation status | ||||||
Yes | 6 | 10 | 0.0001 | 5 | 7 | 0.0001 |
No | 7 | 19 | 0.0001 | 6 | 16 | 0.0001 |
Chemotherapy | ||||||
Yes | 8 | 11 | 0.0001 | 7 | 10 | 0.0001 |
No | 6 | 20 | 0.0001 | 5 | 16 | 0.0001 |
Metastatic site | ||||||
Bone | ||||||
Yes | 6 | 8 | 0.0001 | 4 | 6 | 0.0001 |
No | 8 | 20 | 0.0001 | 7 | 17 | 0.0001 |
Brain | ||||||
Yes | 5 | 6 | 0.0001 | 4 | 4 | 0.0001 |
No | 8 | 18 | 0.0001 | 7 | 14 | 0.0001 |
Liver | ||||||
Yes | 5 | 5 | 0.0001 | 4 | 4 | 0.0001 |
No | 8 | 18 | 0.0001 | 7 | 15 | 0.0001 |
Lung | ||||||
Yes | 6 | 9 | 0.0001 | 5 | 6 | 0.0001 |
No | 9 | 21 | 0.0001 | 8 | 19 | 0.0001 |
Grade | ||||||
Well, moderate | 10 | 17 | 0.0001 | 9 | 23 | 0.0001 |
Poor, undifferentiated | 8 | 20 | 0.0001 | 8 | 19 | 0.0001 |
Income | ||||||
< $60,000 | 7 | 15 | 0.0001 | 6 | 11 | 0.0001 |
> $60,000 | 7 | 17 | 0.0001 | 6 | 13 | 0.0001 |
Tumor size | ||||||
< 4 cm | 7 | 21 | 0.0001 | 6 | 17 | 0.0001 |
4-7 cm | 8 | 20 | 0.0001 | 6 | 18 | 0.0001 |
>7 cm | 7 | 14 | 0.0001 | 6 | 11 | 0.0001 |
