Fig. 2 | Scientific Reports

Fig. 2

From: Proteomic profiling of plasma extracellular vesicles identifies signatures of innate immunity, coagulation, and endothelial activation in septic patients

Fig. 2

Characterization of plasma EVs from septic patients and health controls. The concentration of EVs (A) and the mean EV size (B) isolated from the plasma of Healthy control (Control) individuals and septic patients (Sepsis) were quantified using a nanoparticle tracking analysis (Viewsizer 3000, Horiba Scientific). Comparative analysis was conducted based on EV samples from 15 septic patients and 10 HC individuals. The bar in the middle of the dots indicates the mean value. An unpaired t-test was used for the statistical analysis (**: P ≤ 0.01, and ns: not significant). (C) The representative size distribution for two EV samples is presented. (D) Western blot of Alix (PDCD6IP) and CD9 in the EVs isolated from a group of HC individuals and septic patients. Alix: PDCD6IP (Programmed cell death 6-interacting protein), CD9: tetra-spanin membrane protein.

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