Fig. 6 | Scientific Reports

Fig. 6

From: Proteomic profiling of plasma extracellular vesicles identifies signatures of innate immunity, coagulation, and endothelial activation in septic patients

Fig. 6

Cell-type enrichment and pathway analysis of the EV proteins in the M3, M4, M5, M6, and M7 modules. (A, C, E, G, I) Cell-type enrichment analysis for proteins in the modules using the DISCO database, highlighting the top 10 enriched cell types for each module, based on -Log10 (P value). Each bar color represents a specific cell type. (A) is for M3, (C) for M4, (E) for M5, (G) for M6, and (I) for M7. (B, D, F, H, J) KEGG pathway analysis for the modules was performed and the top 10 significant pathway terms were selected for each module based on P value, showing upregulated pathways in red and downregulated pathways in blue. (B) is for M3, (D) is for M4, (F) is for M5, (H) is for M6, and (J) is for M7.

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