Table 1 Summary of existing studies integrating BC and DL models in healthcare applications.

From: Blockchain enabled deep learning model with modified coati optimization for sustainable healthcare disease detection and classification

Authors

Techniques

Metrics

Dataset

Major findings and limitations

Ragab et al.11

BC, SCA, DFFNN, AFSA, Signcryption Technique

Accuracy, Precision, Recall, F1-Score

Heart Statlog, Pima Indians Diabetes, and EEG Eye State

BPEHR-SCADL outperforms existing methods in secure and accurate EHR classification

Ali et al.12

BC, Hybrid DL, Permissions-based Framework

Scalability, Security, Data Interoperability, Diagnostic Accuracy, Privacy Preservation

Standard Dataset

The framework improves secure, scalable healthcare data management and accurate decision-making

Alanazi et al.13

BCODL-SDSC, FOLS, TSO, ARO, SRNN

Accuracy, Sensitivity, Specificity, F-Score, MCC

Benchmark Medical Image Dataset

The model attained secure data sharing and classification with a peak accuracy of 99.11%

Alamro et al.14

BHS-ALOHDL, ALO-FSS, CNN-LSTM, FPA

Accuracy, Precision, Recall, F-Score, AUC-Score

Two Benchmark Dataset

The method enhanced intrusion detection accuracy and processing speed in IoT healthcare systems

Mohananthini, Rajeshkumar, and Ananth15

BGJOA-DLSMTD, GJOA, Homomorphism Encryption, BC, BOA, DBN, CapsNet-based Feature Extraction

Accuracy, Sensitivity, Specificity, F-Score, MCC

ISIC Dataset

The method attained superior performance in medical image encryption, secure transmission, and disease diagnosis

Qu et al.16

Quantum BC and NN, Controlled Quantum Walk Hash Function, Quantum Authentication Protocol, HQCNN

TR/TS Accuracy, Detection Stability

Standard Dataset

HQCNN attains high accuracy and stability, outperforming classical CNN with greater robustness to quantum noise

Naveen, Dhivya, and Jenefa17

DenseNet Architecture, BC, TL, Bottleneck and Transition Layers

Accuracy, Precision, Recall, F1-Score

Dermoscopic Image Dataset

DenseNet and BC integration improves melanoma detection accuracy and efficiency

Kateb et al.18

ESHCS-DLJSO, Min–Max Normalization, BFOA, CNN-LSTM-Attention, JSO

Accuracy

IoT Healthcare Security Dataset

The model attains a superior accuracy of 99.43%, enhancing disease detection and IoT healthcare security

Rahal et al.19

DL, BC, Model Ensembling, Secure Model Sharing

Accuracy

Breast Cancer Dataset

The BC-based ensembling approach improves diagnostic accuracy and protects patient privacy

Hota et al.20

CNN

Accuracy, Precision, Recall, F1-Score

Standard Dataset

The system ensures privacy and prevents data breaches while attaining 92% accuracy in diagnosis

Rokade and Mishra21

BC, LeNet, TCIO, DeepJoint Segmentation with Kumar-Hassebrooks Distance

Accuracy, True Positive Rate, True Negative Rate, False Negative Rate, False Positive Rate

Benchmark Dataset

The model attained high accuracy and a robust detection rate for classifying skin diseases

Islam et al.22

ML, Predictive Analytics, AI, DL

Diagnostic Accuracy, Disease Prediction, Resource Optimization

Commonly Used Public Datasets

ML and AI improve disease detection and healthcare efficiency, but privacy, security, and bias issues remain

Shammi et al.23

ML, DL, BC

Disease Diagnosis, Data Security, Patient Privacy

Public Dataset

AI improves diagnosis and monitoring, while BC secures data and privacy

Matlo et al.24

PoWV-XAI, BC

Delay Control, Energy Consumption, Cost Efficiency, Security Validation

Various Dataset

PoWV-XAI enhances explainability and optimizes delay, energy, cost, and security

Khan and Jilani25

RSA, Blowfish Encryption, BC, ANN, CNN, RNN

Accuracy, Security

Heart Disease Data

The model ensures secure, accurate heart disease prediction (0.9941) while preserving privacy in cloud healthcare systems

Kulkarni et al.26

BC-based IoT, Privacy Matrix Generation, AHPO, Deep Maxout Network, SpinalNet

Accuracy, True Positive Rate, True Negative Rate

Healthcare Data

The model ensures private, accurate healthcare classification with high TPR and TNR

Gupta, Kumar, and Gupta27

FL, BC, DenseNet-201, FedAvg Aggregation, IPFS for Storage

Accuracy, Precision, Recall, F1-Score

Heterogeneous Datasets

The FL-BC framework detects lung disease with 90% accuracy while preserving data privacy

Ahmed et al.28

DL, PSO-BioBERT, Named Entity Recognition, Relation Extraction

NER and RE Accuracy, NER and RE F1-Score, Accuracy Gain over Bi-LSTM and BERT

Medical Dataset

The technique improves NER and RE performance, improving smart healthcare data analysis and decision-making

Dubey, Kapoor, and Saraswat29

Hybrid Learning Methods, Biological Feature Selection, BC-based Data Storage, Bidirectional LSTM, Time-series Data Categorization, Alzheimer’s Diagnosis

Multi-disease Prediction, Intrusion Detection, Alzheimer’s Diagnosis Accuracy, Image Segmentation Quality

EEG Data Dataset

The method improves early disease diagnosis and risk reduction using advanced algorithms and image analysis

Chougule et al.30

Entropy, Correlation Coefficient

Accuracy

Healthcare Dataset

The model enhances healthcare prediction accuracy and data security using advanced techniques

Al-Marridi, Mohamed, and Erbad31

BC, DRL, Multi-Agent Q-Learning, MDP, Computational resource optimization, Cooperative-competitive decision-making, QoS Optimization

Decision-making speed, Resource Utilization, Latency Minimization, Cost Minimization, Security Maximization, Qos Adherence

Simulated Healthcare Data

IP-HealthChain improves decision speed, mitigates latency, optimizes resources, enhances security, and cuts costs

Pradhan et al.32

ML, NN, HIoT, EHR, Security Enhancements, QoS

Security Improvement, QoS Enhancement, Accuracy of ML Models

Benchmark Dataset

ML applied to HIoT can improve security and QoS in EHR systems