Table 3 All treatment-related adverse events(TRAEs) in the SAS.

From: Anlotinib plus camrelizumab and chemotherapy as first-line treatment in patients with advanced esophageal squamous cell carcinoma

TRAEs

No.(%) of patient

TCCA(n = 30)

TCC(n = 30)

Any grade

≥G3

Any grade

≥G3

ALL TRAEs

30(100)

12(40.0)

30(100)

8(26.7)

Leukopenia

14(46.7)

4(13.3)

7(23.3)

2(6.7)

Neutropenia

12(40)

5(16.7)

8(26.7)

1(3.3)

Lymphopenia

6(20)

2(6.7)

4(13.3)

1(3.3)

Thrombocytopenia

7(23.3)

3(10)

7(23.3)

3(10)

Rash

7(23.3)

1(3.3)

3(10)

1(3.3)

Nausea/Vomiting

18(60)

0(0)

20(66.7)

2(6.7)

Fatigue

22(73.3)

0(0)

22(73.3)

0(0)

Anemia

11(36.7)

0(0)

17(56.7)

0(0)

Anorexia/Dysgeusia

25(83.3)

1(3.3)

24(80)

1(3.3)

Diarrhea

1(3.3)

0(0)

2(6.7)

0(0)

Numbness/ Hypoesthesia

14(46.7)

0(0)

10(33.3)

0(0)

Alopecia

30(100)

0(0)

30(100)

0(0)

Constipation

13(43.3)

0(0)

17(56.7)

0(0)

Proteinuria

2(6.7)

1(3.3)

0(0)

0(0)

Interstitial pneumonia

2(6.7)

0(0)

1(3.3)

0(0)

T3 reduction

6(20)

0(0)

1(3.3)

0(0)

T3 elevation

4(13.3)

0(0)

6(20)

0(0)

T4 reduction

3(10)

0(0)

0(0)

0(0)

T4 elevation

5(16.7)

0(0)

2(6.7)

0(0)

Myocarditis

5(16.7)

0(0)

6(20)

0(0)

Hypertension

2(6.7)

2(6.7)

0(0)

0(0)

RCCEP

6(20)

0(0)

20(66.7)

1(3.3)

Hypoproteinemia

9(30)

0(0)

5(16.7)

0(0)

AST/ALT Elevation

3(10)

0(0)

3(10)

0(0)

Low sodium/Low potassium

3(10)

0(0)

1(3.3)

0(0)

Myalgia

18(60)

0(0)

22(73.3)

0(0)

Epistaxis

1(3.3)

0(0)

0(0)

0(0)

Venous thrombosis

0(0)

0(0)

1(3.3)

1(3.3)

  1. Data are n (%).RCCEP, reactive cutaneous-capillary endothelial proliferation.