Table 3 All treatment-related adverse events(TRAEs) in the SAS.
TRAEs | No.(%) of patient | |||
|---|---|---|---|---|
TCCA(n = 30) | TCC(n = 30) | |||
Any grade | ≥G3 | Any grade | ≥G3 | |
ALL TRAEs | 30(100) | 12(40.0) | 30(100) | 8(26.7) |
Leukopenia | 14(46.7) | 4(13.3) | 7(23.3) | 2(6.7) |
Neutropenia | 12(40) | 5(16.7) | 8(26.7) | 1(3.3) |
Lymphopenia | 6(20) | 2(6.7) | 4(13.3) | 1(3.3) |
Thrombocytopenia | 7(23.3) | 3(10) | 7(23.3) | 3(10) |
Rash | 7(23.3) | 1(3.3) | 3(10) | 1(3.3) |
Nausea/Vomiting | 18(60) | 0(0) | 20(66.7) | 2(6.7) |
Fatigue | 22(73.3) | 0(0) | 22(73.3) | 0(0) |
Anemia | 11(36.7) | 0(0) | 17(56.7) | 0(0) |
Anorexia/Dysgeusia | 25(83.3) | 1(3.3) | 24(80) | 1(3.3) |
Diarrhea | 1(3.3) | 0(0) | 2(6.7) | 0(0) |
Numbness/ Hypoesthesia | 14(46.7) | 0(0) | 10(33.3) | 0(0) |
Alopecia | 30(100) | 0(0) | 30(100) | 0(0) |
Constipation | 13(43.3) | 0(0) | 17(56.7) | 0(0) |
Proteinuria | 2(6.7) | 1(3.3) | 0(0) | 0(0) |
Interstitial pneumonia | 2(6.7) | 0(0) | 1(3.3) | 0(0) |
T3 reduction | 6(20) | 0(0) | 1(3.3) | 0(0) |
T3 elevation | 4(13.3) | 0(0) | 6(20) | 0(0) |
T4 reduction | 3(10) | 0(0) | 0(0) | 0(0) |
T4 elevation | 5(16.7) | 0(0) | 2(6.7) | 0(0) |
Myocarditis | 5(16.7) | 0(0) | 6(20) | 0(0) |
Hypertension | 2(6.7) | 2(6.7) | 0(0) | 0(0) |
RCCEP | 6(20) | 0(0) | 20(66.7) | 1(3.3) |
Hypoproteinemia | 9(30) | 0(0) | 5(16.7) | 0(0) |
AST/ALT Elevation | 3(10) | 0(0) | 3(10) | 0(0) |
Low sodium/Low potassium | 3(10) | 0(0) | 1(3.3) | 0(0) |
Myalgia | 18(60) | 0(0) | 22(73.3) | 0(0) |
Epistaxis | 1(3.3) | 0(0) | 0(0) | 0(0) |
Venous thrombosis | 0(0) | 0(0) | 1(3.3) | 1(3.3) |