Fig. 5 | Scientific Reports

Fig. 5

From: DNMT3B aggravated renal fibrosis in diabetic kidney disease via activating Wnt/β-catenin signaling pathway

Fig. 5

The demethylation drug 5-Aza reversed the hyperglycaemic effects in high-glucose stimulated RTECs. (A) The protein expression of ECM-related markers (E-cadherin and fibronectin) was assessed via Western blotting using RTECs after stimulation with or without a DNMT inhibitor (5-Aza, 80 µM) for 48 h (n = 3). The data are expressed as means ± SDs. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.000 vs. control.

Back to article page