Fig. 3
From: DDTC-Cu(I) inhibits human osteosarcoma cells growth by repressing MET/PI3K/AKT signaling pathway
(A–D) SaOS2 and U2OS cells were seeded, scratched and incubated with different concentrations of DDTC-Cu(I) for 12 / 24 h. Migration rates were measured by Fiji-4.0.1. Scale bar, 500 μm. (E–G) Representative images of transwell invasion assays in SaOS2 and U2OS. Manual methods were used to quantify invaded cells. Scale bar, 300 μm. SaOS2 and U2OS cells were preprocessed with 0 / 0.5 / 1 µM of DDTC-Cu(I) for 24 h. (The data are depicted as mean ± SD of at least three experimental replicates. P < 0.05 was termed statistically essential, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. the control group).
