Fig. 5

SIAH2-AS1 enhances the function of BC cells lines by promoting Wnt/β-catenin signaling. (A-C) CCK-8 and colony formation assays revealed that after treatment with LiCl, proliferation suppression was restored in MDA-MB-231 and MDA-MB-468 cells lines; (D-G) wound healing and transwell studies showed that LiCl reversed the inhibition of migratory and invasive capacities induced by SIAH2-AS1 knockdown in MDA-MB-231 and MDA-MB-468 cells. *, P < 0.05; **, P < 0.01; ***, P < 0.001.