Fig. 3
From: Simplified kinetic modeling for predicting the stability of complex biotherapeutics
Comparison of kinetic model (blue) against linear regression model (red). Prediction intervals (dashed lines) denote the range within which true values are likely to fall with 95% confidence level. Models were trained by 10 weeks (left) and 9 month (right) experimental stability data (closed circles). Data points used for model validation are shown as empty circles and were not used for model training. Data shown is for DARPin formulation stored at 5 °C. For kinetic model training, data points from 15, 20 25 and 30 °C conditions up to the respective time point were used (data points not shown for clarity reasons).
