Table 7 RNA design benchmark results for the RNAsolo dataset divided by motif type (best values in bold).

From: Comprehensive datasets for RNA design, machine learning, and beyond

RNA design algorithm

Average computing time (s)

Normalized RNAdistance

RNApdist

F1-score

Results for 2248 instances of internal loop motifs successfully solved by each algorithm

 RNAinverse

0.24

0.06

7.73

0.97

 RNAsfbinv

4.17

0.10

8.68

0.85

 INFO-RNA

0.05

0.12

7.65

0.84

 RNARedPrint

7.69

0.13

7.75

0.91

 DSS-Opt

2.13

0.06

7.24

0.96

 DesiRNA

293.50

0.01

6.95

0.99

 Meta-LEARNA

4.86

0.07

7.13

0.94

 

8.13

   

Results for 327 instances of higher-cardinality junction motifs successfully solved by each algorithm

 RNAinverse

1.31

0.06

20.59

0.97

 RNAsfbinv

14.42

0.11

21.72

0.88

 INFO-RNA

0.16

0.14

19.43

0.85

 RNARedPrint

8.92

0.22

21.08

0.84

 DSS-Opt

2.33

0.03

19.82

0.98

 DesiRNA

385.78

0.02

18.75

0.99

 Meta-LEARNA

5.88

0.04

19.27

0.95

Results for 160 instances of 3-way junction motifs successfully solved by each algorithm

 RNAinverse

1.91

0.08

21.21

0.96

 RNAsfbinv

19.72

0.14

22.60

0.84

 INFO-RNA

0.17

0.20

20.23

0.78

 RNARedPrint

9.37

0.28

22.54

0.80

 DSS-Opt

2.91

0.04

19.33

0.97

 DesiRNA

384.37

0.02

18.12

0.98

 Meta-LEARNA

6.65

0.04

18.93

0.96

Results for 154 instances of 4-way junction motifs successfully solved by each algorithm

 RNAinverse

0.74

0.04

19.70

0.98

 RNAsfbinv

8.73

0.07

20.35

0.92

 INFO-RNA

0.13

0.09

18.14

0.91

 RNARedPrint

8.44

0.15

19.12

0.90

 DSS-Opt

1.76

0.02

19.76

0.99

 DesiRNA

386.64

0.01

18.81

0.99

 Meta-LEARNA

4.78

0.03

19.13

0.94