Fig. 3

Single-cell analysis of PDGs for each DP (Mi-M-S) and RP (S-M-Mi) group. (A) UMAP of samples from DP patients, colored by cell types. (B) UMAP and ridge plots of AREG and IFI27, whose expression levels increase and decrease, respectively, during DP. (C) UMAP of samples from RP patients, colored by cell types. (D) UMAP and ridge plots of IFI27 and IL-1B, whose expression levels decrease and increase, respectively, during RP. (E) Boxplots for the expression levels of genes with tendencies related to severity progression. (F) Boxplots for the expression levels of ISGs. To enhance visualization, cells with zero expression for each gene are excluded from the ridge and boxplots.