Fig. 5
From: The effects of systemic and sustained hypoxia on orthodontic tooth movement in rats
Immunohistochemistry (IHC) sections of Ki67 staining of the mesial root of M1, including the distal and mesial side of the non-OTM group and the tension and compression sides of the OTM group. The quantitative results of the Ki67-positive ratio (%) show significant differences between tension and compression areas in both control-OTM and hypoxia-OTM groups. The control groups have consistently higher numbers of Ki67-positive cells compared to their hypoxic counterparts in the non-OTM and OTM groups. (A) Representative image of IHC staining for Ki67. (B) Quantitative comparison of Ki67-positive cells (%) between groups. The Ki67-positive ratio in the hypoxia-OTM group is significantly lower on both the tension and compression sides compared with that in the control-OTM group. Scale bar, 100 μm. n = 6; mean ± SD; * p < 0.05.
