Table 2 Observations from Heterogeneity and Pleiotropy Tests in Mendelian Randomization analysis.
Outcome | Exposure | Heterogeneity test | Q | Q_df | Q_Pval | Egger_intercept | Pval |
|---|---|---|---|---|---|---|---|
AD | GBM | MR Egger | 3.81943321 | 5 | 0.57569505 | 0.006197692 | 0.7590844 |
Inverse variance weighted | 3.92438015 | 6 | 0.68690922 | ||||
GBM | AD | MR Egger | 2.26205198 | 11 | 0.99734307 | 0.1269191 | 0.09245345 |
Inverse variance weighted | 5.65786487 | 12 | 0.93233771 | ||||
AD | Parental history of AD | MR Egger | 63.4257537 | 8 | 9.87E-11 | -0.03659904 | 0.1705198 |
Inverse variance weighted | 81.4042207 | 9 | 8.50E-14 | ||||
GBM | Parental history of AD | MR Egger | 3.65474526 | 9 | 0.93263348 | 0.1032982 | 0.2029453 |
Inverse variance weighted | 5.54026893 | 10 | 0.85229728 |
