Fig. 8 | Scientific Reports

Fig. 8

From: The key regulation of LncRNA MALAT during reprogramming of primary mouse hepatocytes into insulin producing cells

Fig. 8

Functional analysis after IPCs transplantation in T1DM mice. (A) Fasting blood glucose levels of mice, glucose levels were monitored using tail-vein blood samples. (B, C) Serum TC, TG, HDL-C, LDL-C, and insulin levels at the end of the experiment. (n = 5, *p < 0.05 versus control group, #p < 0.05 versus T1DM group, respectively). (D) Histological section of pancreas tissue. (E) Immunofluorescence staining of β-cell markers (Insulin) and α-cell markers (Glucagon) in pancreas tissue. (F)Immunofluorescence staining of β-cell markers (Insulin and PDX1) in transplanted kidney grafts, and statistical results of the overlapping fluorescence intensity. All fluorescently stained cells were observed under ×20 objective, and representative images are shown. (n = 5, *p < 0.05 T1DM + IPCs group, respectively).

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