Table 2 Comparison between glaucoma patients with and without laminar VD change after glaucoma surgery.

From: Microvasculature recovery in lamina cribrosa and peripapillary sclera after glaucoma surgery and its impact on visual field progression

Variables

Laminar VD change (+)

(n = 12)

Laminar VD change (−)

(n = 62)

P value

Age, y

53.33 ± 17.13

51.61 ± 20.02

0.761*

Female, n (%)

4 (33.3%)

27 (43.5%)

0.373†

Diagnosis

  

0.398†

 POAG, n (%)

8 (66.7%)

43 (69.4%)

 

 JOAG, n (%)

0

6 (9.7%)

 

 Others, n (%)

4 (33.3%)

13 (21.0%)

 

Spherical equivalent, diopters

− 1.91 ± 2.65

− 3.51 ± 4.31

0.174*

Axial length, mm

24.36 ± 1.10

25.67 ± 1.94

0.005*

Central corneal thickness, μm

521.44 ± 24.27

547.42 ± 37.78

0.016*

Preoperative IOP, mmHg

32.29 ± 5.68

31.11 ± 7.42

0.541*

Postoperative IOP, mmHg

13.24 ± 3.23

14.90 ± 3.25

0.124*

Change of IOP, %

− 70.40 ± 16.46

− 55.69 ± 25.35

0.101*

Average pRNFL thickness, μm

64.77 ± 13.04

65.33 ± 12.49

0.906*

Average mGC/IPL thickness, μm

62.55 ± 9.15

60.74 ± 12.86

0.616*

MD of VF, dB

− 12.71 ± 8.15

− 15.19 ± 9.42

0.470*

PSD of VF, dB

8.22 ± 4.45

9.17 ± 8.83

0.355*

Preoperative laminar VD, %

11.58 ± 5.68

13.72 ± 8.40

0.286*

Change of laminar VD, %

21.92 ± 7.37

1.77 ± 4.49

 < 0.001*

Preoperative PPS VD, %

13.75 ± 8.77

9.32 ± 7.44

0.123

Change of PPS VD, %

0.33 ± 0.65

5.46 ± 8.54

 < 0.001*

Follow-up period, y

0.66 ± 0.02

0.65 ± 0.02

0.367*

  1. IOP, intraocular pressure; pRNFL, peripapillary retinal nerve fiber layer; mGC/IPL, macular ganglion cell-inner plexiform layer; VF, visual field; MD, mean deviation; PSD, pattern standard deviation; dB, decibel; PPS, peripapillary sclera; VD, vessel density; FAZ, foveal avascular zone.
  2. Data are mean ± standard deviation unless otherwise indicated.
  3. *Student’s t-test.
  4. †Chi-square test.
  5. Factors with statistical significance are shown in bold.
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