Fig. 6
Comparison of the average speed by cell (µm·min−1) of MSCs grown on the different substrates. The plots are grouped comparing parameters of interest: (a) polymer (stiffness), (b) LAR microstructures, (c) presence or not of ME nanostructure, and (d) aspect ratio. (e) Directionality ratio of MSCs cultured on the different groups of substrates comparing LAR microtopographies and their homologous hierarchies with some representative cell tracks. α-values obtained from the MSCs migration assay on the different substrates comparing (f) presence of ME nanostructure also in hierarchical combination and (g) aspect ratio. Statistical comparisons were made by means One-way ANOVA followed by Holm-Šidak post-hoc analysis. Significant differences were established by asterisks (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001) and non-significant (ns) for the corresponding comparisons.
