Fig. 1 | Scientific Reports

Fig. 1

From: Substrate binding and coupled mechanisms of Vps4p substrate recruitment and release from autoinhibition

Fig. 1The alt text for this image may have been generated using AI.

Structure of Vps4 hexamer and peptide coordination. a, Peptide-8 bound to the Vps4p translocation groove (PDB: 6AP1)15. b, Close-up of class 1 and 2 pockets created between adjacent subunits W206 (orange and yellow) and M207 (orange and yellow), respectively, with charged contributions from K205 (blue) and E247 (red), respectively. a and b were generated using PyMOL, version 2.0 (Schrödinger, LLC) (https://storage.googleapis.com/pymol-storage/installers/index.html).

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