Fig. 2 | Scientific Reports

Fig. 2

From: Bithionol is ineffective in a mouse model of S. aureus implant-associated osteomyelitis despite potent in vitro activity

Fig. 2The alternative text for this image may have been generated using AI.

Bacterial load in bone fragments and from implants after 5 days of treatment in a murine model of S. aureus IAOM. Each datapoint represents the mean log CFU/ml of triplicates from each sample (bone or implant). a: bacterial load in bone fragments. b: biofilm bacterial load on implants. NaCl = NaCl (0.9%) in water, BIT = 30 mg/kg/12 h bithionol, MOX = 10 mg/kg/12 h moxifloxacin, DAP = 50 mg/kg/24 h daptomycin. Bars represent mean ± SD. n = 10/group. Brackets represent pairwise comparison (one-way ANOVA, p < 0.05 = significant).

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