Fig. 1 | Scientific Reports

Fig. 1

From: Tapping the untapped: type II L-asparaginase from marine crustacean-derived Chryseomicrobium amylolyticum as a potential bio better for blood cancer therapy

Fig. 1

Plackett-Burman (PB) design-based media optimization for C. amylolyticum type II L-asparaginase production. (A) Pareto Chart showing the order of significance of the variables affecting the enzyme production. Nine independent factors were screened with two unassigned/ dummy parameters. The independent factors are: A: L-asparagine (mM), B: medium pH, C: incubation temperature (°C), D: Inoculum (%), E: Agitation (rpm), F: K2HPO4 (%), G: NaCl (%), H: Peptone (%), J: NH4Cl (mM), K: Dummy 1, L: Dummy 2. Orange bars denote those variables with significant (p < 0.05) positive effects and blue bars denote those variables with significant (p < 0.05) negative effects; (B): Correlation plot of predicted values against actual values of the enzyme activity; (C): Normal probability plot of the internally studentized residuals.

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