Fig. 9

High-resolution images from microglia in the inner retina (A; GCL) and RPE (B). CtB is only internalized by RPE microglia (B) but not inner retinal ramified microglia contrary to the direct contact with the CtB-A555 particles of these cells (A). In the RPE, Iba1+ cells internalized the dye and clearly expressed JamB tight junction protein (blue arrowheads) (Suppl. Video 1 for rotation of B); JamB is normally expressed only by RPE cells (blue, highlighted with light blue dots).