Table 1 Univariate and multivariate Cox regression analyses are used to assess the impact of key targets on patient prognosis.

From: Exploring the mechanism of Naringenin in the treatment of hepatocellular carcinoma based on mRNA sequencing and experimental validation

Characteristics

Total(N)

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

IGFBP3

373

    

Low

187

Reference

 

Reference

 

High

186

1.670 (1.178–2.368)

0.004

1.441 (0.986–2.105)

0.059

CHRNA7

373

    

Low

186

Reference

   

High

187

1.286 (0.910–1.817)

0.154

  

PGF

373

    

Low

186

Reference

 

Reference

 

High

187

1.780 (1.251–2.533)

0.001

1.295 (0.878–1.909)

0.193

CA9

373

    

Low

187

Reference

 

Reference

 

High

186

1.966 (1.382–2.797)

< 0.001

1.493 (1.008–2.213)

0.046

KLK1

373

    

Low

187

Reference

   

High

186

1.385 (0.979–1.960)

0.066

  

AKR1C3

373

    

Low

187

Reference

 

Reference

 

High

186

1.630 (1.150–2.310)

0.006

1.544 (1.077–2.214)

0.018