Table 2 Antixodant potencial of 12a–j.

From: Development of mercapto-phenyl-1,2,4-triazole bearing thio-quinoline as a novel class of tyrosinase inhibitors: an in vitro and in silico study

Compounds

R

IC50 (µM)

12a

Phenyl

107.18 ± 3.49

12b

2-Chlorophenyl

105.93 ± 1.72

12c

3-Chlorophenyl

94.46 ± 4.61

12d

4-Chlorophenyl

116.15 ± 1.89

12e

2,4-Dichorophenyl

123.74 ± 1.01

12f

4-Methoxyphenyl

98.91 ± 4.83

12g

4-Methylphenyl

120.26 ± 3.91

12h

2-Methyl phenyl

130.53 ± 10.61

12i

2,3-Dimethyl phenyl

142.25 ± 1.39

12j

Ethyl phenyl

102.36 ± 3.33

Quercetin[a]

–

18.56 ± 2.19

  1. Values represent means ± SD of three independent experiments.
  2. [a]Positive control.
Back to article page