Fig. 4 | Scientific Reports

Fig. 4

From: Enhanced activity localization and microscale dosimetry in alpha-emitter radiopharmaceutical therapy using integrated autoradiography and histological imaging

Fig. 4

Coregistration quality when using 3 or 1 sections per slide for a coregistration. Images showing activity (color) superimposed on gray-scale (P&H). Small registration errors are resolved when using 3 sections (A), but not when using a single section (B) for registration. Significant mismatches shown along the outside tissue border in (B) (circles). This is a typical example in which the activity does not perfectly follow the tissue outline due to additional non-tumor (e.g. connective) in the section. Tumor recording from 3 days pi. P&H image is displayed in gray scale to increase clarity.

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