Table 2 Differentially abundant miRNAs according to evaluation with the interaction model.

From: Profiling of the microRNA transcriptome in feline whole blood

Interaction model

Breed

All cats (n = 12)

Healthy cats (n = 6)

10 row sum counts

10 row sum counts

5 row mean counts

miRNA

log2 FC

padj

miRNA

log2 FC

padj

miRNA

log2 FC

padj

let-7f.-5p

1.8†*

0.034

let-7f.-5p

1.8

0.034

miR-151a-3p

− 1.1

0.023

miR-151a-3p

− 1.1

0.034

miR-151a-3p

-1.1

0.034

miR-3613-5p

3.3

0.023

miR-3613-5p

3.3†*

0.034

miR-3613-5p

3.3

0.034

let-7f.-5p

1.8

0.026

miR-98-5p

1.7†*

0.037

miR-98-5p

1.7

0.037

miR-98-5p

1.7

0.027

miR-330-5p

− 1.4

0.058

miR-330-5p

-1.4

0.058

miR-330-5p

− 1.4

0.039

miR-26b-5p

1.0†*

0.079

miR-26b-5p

1.0

0.079

miR-26b-5p

1.0

0.065

A2_1436

− 5.9

0.096

A2_1436

− 5.9

0.096

   

Heart status in NFO (n = 6)

5 row mean counts

  

miRNA

log2 FC

padj

  

miR-204-5p

− 3.8†

0.0624

  
  1. Results show significant miRNAs following evaluation with different prefiltering steps of the data. A Benjamini-Hochberg (BH) adjusted p-value (padj) of ≤ 0.1 was considered significant. Trends validated in additional WB-samples for similar group-comparison are marked with †, and if statistically significant also marked with *. FC = fold change; NFO = Norwegian Forest cat.
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